The combination of RegenPRP® and RegenATS® offers different application possibilities. By adding ATS to the liquid PRP, different strengths can be achieved. In this way, Regen PRP can be brought into the optimal state and shape for the respective application. The result is a leukocyte-reduced platelet gel (platelets embedded in the fibrin matrix), which can also be used as a dimensionally stable membrane if required. The leukocyte-reduced platelet gel has adhesive properties and falls under the scope of tissue engineering.
The addition of autologous thrombin serum (ATS) to the Regen PRP physiologically starts the coagulation process and thus enables the production of a leukocyte-reduced platelet gel.
Autologous Thrombin Serum (ATS) converts soluble fibrinogen into fibrin monomers, which polymerize into a clot.
This natural process induces the formation of a three-dimensional fibrin matrix in which the platelets are embedded. This enables long-lasting growth factor delivery at the treatment site and the matrix serves as a scaffold for new tissue reconstruction.
The coagulation process is a complex cascade of reactions that causes the thrombin to convert soluble fibrinogen into insoluble fibrin molecules that form the fibrin clot. If calcium is added, this accelerates the process and the fibrin structure is strengthened.